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Include a digital thermometer with min/max memory to verify the internal temperature stayed within range throughout transit

For ultra-orphan drugs at prices of $300,000 to $500,000 per patient year, seven years of exclusivity on a 3,000-patient market can generate more than $1 billion in cumulative revenue

In November 2025, the administration announced deals with Eli Lilly and Novo Nordisk to provide their GLP-1s at reduced prices

no licensed dosage has been established

That said, both are considered effective, with similar response ratesmeaning that most people will lose weight on either drug

The C57/BL-6 mice were used for the knockout construction